According to the findings of a new study, for every three cases where high doses of statins like Lipitor are successful in lowering the risk of cardiovascular events, there may be one instance of new-onset diabetes. This research adds to previous information about the potential risk of Type 2 diabetes linked to Lipitor, Crestor and other popular cholesterol drugs, which has raised concerns about the safety of the medications. If you believe you have been adversely affected by side effects of Lipitor, our consumer advocates at the Consumer Justice Foundation can help. We are dedicated to protecting the rights of consumers harmed by Big Pharma, and can help put you in touch with an experienced Lipitor attorney in your area. With a qualified lawyer on your side, you can protect your legal rights and discuss the benefits of filing a product liability lawsuit against Lipitor maker, Pfizer.
In the study, published in the medical journal Diabetes, Obesity and Metabolism, researchers from the University of Alabama and the Mid-America Heart Institute at Saint Luke’s Hospital found a “definite but small” increase in the risk of diabetes among patients taking Lipitor and other cholesterol-lowering medications known as statins. Before coming to this conclusion, the researchers examined a series of studies involving a number of different cholesterol medications, and identified a series of larger studies indicating that, not only does the risk of diabetes with statin use exist, but it is statistically significant.
There has long been a difference of opinions regarding the potential risk of diabetes associated with Lipitor, Crestor and other statin drugs. This is evidenced by the fact that researchers involved in the Diabetes study found a 34% increased risk of diabetes with Lipitor use in one study, and no increased risk at all in another. “Because of the conflicting outcomes, even in these large studies, several large meta-analyses have been performed to try to prove or disprove whether statins as a class cause conversion to diabetes,” the researchers wrote.
Although the factor that actually increases diabetes risk among statin users remains unknown, researchers have theorized that the connection may be associated with a drop in ubiquinone levels, especially at higher doses of the medications, which can lead to a delayed insulin release. “There seems to be a definite but small increase in the development of diabetes with statin therapy, which generally occurs in those predisposed to develop diabetes through the presence of diabetogenic risk factors,” the researchers wrote in their conclusion. “With statin therapy the risk of developing diabetes is far outweighed by the statin-induced decrease in cardiac events.”
This diabetes study comes just two months after new guidelines introduced by the American Heart Association and American College of Cardiology would potentially put millions of Americans on cholesterol drugs like Lipitor and Crestor indefinitely. According to the recommendations, doctors should prescribe statins exclusively to lower cholesterol levels and disregard cholesterol goal numbers, which would potentially keep patients on the medications permanently. The new guidelines have been heavily challenged by those who believe that the “statinization” of America could result in a medical disaster, especially considering the potential risk of diabetes linked to the drugs.
Statins like Lipitor are among the best-selling drugs in the United States, and they function by blocking the body’s creation of cholesterol, which is a major contributor to coronary artery disease. Unfortunately, mounting research has identified an increased risk of serious side effects potentially tied to statin drugs, including diabetes, kidney problems and muscle damage. In February 2012, the FDA required the manufacturers of statin drugs like Lipitor and Crestor to add new warnings to their labels about the effect of the medications on blood glucose levels. However, some critics have argued that the warnings are not strong enough for certain drugs, suggesting that consumers should be provided with more information about the potential link between Lipitor and diabetes side effects.
As more information comes to light about this side effect risk, hundreds of Lipitor diabetes lawsuits have already been filed against Pfizer throughout the United States, on behalf of consumers who believe they have been adversely affected by the cholesterol drug, and more are expected to be filed in the future. If you have developed Type 2 diabetes, and you believe the statin drug Lipitor to be the cause, contact a knowledgeable Lipitor attorney in your area to discuss your legal options. You may have grounds to file a product liability lawsuit against Pfizer, in order to pursue financial compensation for your injuries, medical bills, and pain and suffering.
[box type=”note” align=”aligncenter” ]Source: http://onlinelibrary.wiley.com/doi/10.1111/dom.12254/abstract[/box]