A new study has indicated a link between side effects of popular over-the-counter pain relievers like Motrin, Advil and Aleve, and an increased risk of potentially life-threatening blood clots. In the study, published last week in the medical journal Rheumatology, researchers from Columbia University suggest that the use of medications known as non-steroidal anti-inflammatory drugs (NSAIDs) may increase a patient’s risk of suffering deadly venous theomboembolism (VTE) complications like deep vein thrombosis (DVT) or pulmonary embolism. If you believe you have been harmed by a side effects of a potentially dangerous pharmaceutical drug, contact a knowledgeable product liability attorney today for legal help.
Researchers involved in the NSAID study conducted an analysis of six studies including 21,401 VTE events, and concluded that individuals taking NSAIDs faced an 80% increased risk of experiencing a dangerous blood clot. “Our study demonstrated a statistically significant increased risk of VTE among NSAID users,” the researchers wrote. “This finding has important public health implications given the prevalence of NSAID use in the general population.”
NSAIDs like Aleve and Advil are among the most widely-used over-the-counter pain relievers in the United States, and this research raises serious concerns about the abundant and often casual use of the potentially dangerous drugs. The findings of this study echo previous concerns regarding the potential side effects of Tylenol, one of the most trusted pain relievers in North America. According to research, people who take too much Tylenol, or take more than one drug containing Tylenol’s active ingredient acetaminophen, may have a significantly increased risk of suffering liver damage or liver failure.
Despite their widespread use, NSAID medications have been linked to a number of serious health problems in recent years, including internal bleeding and cardiovascular complications. Another study published earlier this year found that NSAID drugs can increase a patient’s risk of atrial fibrillation by up to 84%, and some of the popular pain relievers have also been connected to an increased risk of heart attacks. The NSAID painkiller Vioxx, for example, was recalled nearly a decade ago, after researchers linked the drug to a three-times increased risk of heart attack.
Venous thromboembolism occurs when a blood clot develops in the veins, which can travel to the legs and cause deep vein thrombosis, or travel to the heart and lungs, resulting in a potentially deadly pulmonary embolism. “This is the first systematic review and meta-analysis of published observational studies assessing the risk of VTE among NSAIDs users. There are some limitations, however, such as the fact that all NSAIDs are evaluated as one group in this study but not all individual NSAIDs may increase the risk of VTE,” the researchers wrote.
“Why NSAIDs may increase the risk of VTE is unclear,” the researchers concluded. “Physicians should be aware of this association and NSAIDs should be prescribed with caution, especially in patients already at a higher risk of VTE.” If you took an NSAID drug like Aleve, Motrin or Advil, and you have since suffered a venous thromboembolism event like deep vein thrombosis or pulmonary embolism, our consumer advocates at the Consumer Justice Foundation can help. We are dedicated to protecting the rights of consumers harmed by dangerous drugs, and can help put you in touch with a qualified drug injury lawyer today.
[box type=”note” align=”aligncenter” ]Source: http://rheumatology.oxfordjournals.org/content/early/2014/09/22/rheumatology.keu408.abstract[/box]